THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
PARK, YONG ILKR,박용일,CHOI, JI WONKR,최지원,SOHNG, JAE KYUNGKR,송재경,LEE, JI SUNKR,이지선
申请号：
KR1020140144704
公开号：
KR1020160049079A
申请日:
2014.10.24
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a composition for inhibiting the proliferation and the differentiation of adipocytes, comprising 7&prime,8&prime-dihydroxyflavone. The composition for inhibiting the proliferation and the differentiation of adipocytes of the present invention has no side effects which were exhibited in the conventional pharmaceutical composition, reduces specifically adipocytes, and inhibits the differentiation into the adipocytes from preadipocyte cells. In addition, the composition has effects in reducing the activation of MAPK and the accumulation of active oxygen inside the adipocytes, by promoting the expression of antioxidant enzyme. Therefore, the composition can be efficiently used as a pharmaceutical composition for preventing or treating obesity, or a health functional food for preventing or alleviating obesity.COPYRIGHT KIPO 2016본 발명은 7′8′-디하이드록시플라본(7′8′-Dihydroxyflavone)을 포함하는 지방세포 분화 및 증식 억제용 조성물에 관한 것으로, 본 발명의 지방세포 분화 및 증식역제용 조성물은 종래 약학적 조성물에 나타났던 부작용이 없으면서, 지방세포만을 특이적으로 감소시키고, 지방전구세포에서 지방세포로의 분화를 억제할 수 있으며, 항산화 효소의 발현을 촉진시켜, 지방세포 내 활성산소 축적 및 MAPK의 활성을 감소시키는 효과가 있으므로, 비만 예방 또는 치료용 약학적 조성물 또는 비만 예방 또는 개선용 건강기능식품으로 유용하게 활용될 수 있다.
