ЛИ Адриенна (US),ЭБИ Джексон (US),ДЕМУТ Питер К. (US)
申请号：
RU2017112022
公开号：
RU2017112022A
申请日:
2015.09.11
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
The present invention provides novel and inventive drug delivery systems with higher loading capability, a capacity to sequester high tumors levels of both hydrophobic and hydrophilic agents simultaneously, and longer release profiles. Some aspects of these delivery systems include compositions including stabilized multilamellar lipid vesicles having crosslinked lipid bilayers (referred to herein as inter-bilayer-crosslinked multilamellar vesicles or ICMV) covalently conjugated to an agent (e.g., an antigen).
