Kristi A. LEONARD,Kent BARBAY,James P. EDWARDS,Kevin D. KREUTTER,David A. KUMMER,Umar MAHAROOF,Rachel NISHIMURA,Maud URBANSKI,Hariharan VENKATESAN,Aihua WANG,Ronald L. WOLIN,Craig R. WOODS,Anne FOURIE
申请号:
HK16101837.7
公开号:
HK1213887A
申请日:
2016.02.18
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.