A drug for lowering blood LDL, which is represented by the general formula (I) (R1 is a hydrogen atom or the following formula (II) (R3 is a hydrogen atom, a C1-6 alkyl group, etc., W1 to W5 are CR4 to CR8 (R4 to R8 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, etc., and 0 to 2 of them may be replaced with a nitrogen atom), and R2 represents a C1-6 alkoxy group, C1-6 A pharmaceutical comprising a compound represented by an alkylthio C1-6 alkoxy group, C1-6 alkylsulfinyl C1-6 alkoxy group, etc.) as an active ingredient.血中ＬＤＬを低下させる医薬であって、一般式（I）（Ｒ１は水素原子又は次式（II）（Ｒ３は水素原子、Ｃ１－６アルキル基など、Ｗ１～Ｗ５はＣＲ４～ＣＲ８（Ｒ４～Ｒ８は水素原子、ハロゲン原子、Ｃ１－６アルキル基など）を示し、ただしそれらのうちの０～２個は窒素原子に置き換えてもよい）であり、Ｒ２はＣ１－６アルコキシ基、Ｃ１－６アルキルチオＣ１－６アルコキシ基、Ｃ１－６アルキルスルフィニルＣ１－６アルコキシ基など）で表される化合物を有効成分として含む医薬。
