Bollu, Venkataiah,Breitenbucher, James,Kaplan, Alan,Lemus, Robert,Lindstrom, Andrew,Vickers, Troy,Wilson, Mark E.,Zapf, James,Weinhouse, Michael I.
申请号：
AU2018202148
公开号：
AU2018202148A1
申请日:
2018.03.26
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018202148A120180419.pdf#####1: rbr Interwoven NRPortbl DCC RBR 16704567_l.docx-26 03/2018 ABSTRACT The invention provides a chemical entity of Formula (I), and compositions comprising such chemical entities； methods of making them； and their use in a wide range of methods, including metabolic and reaction kinetic studies, detection and imaging techniques, and 5 radioactive treatments； and therapies, including inhibiting PDE4, enhancing neuronal plasticity, treating neurological disorders, providing neuroprotection, treating a cognitive impairment associated with a CNS disorder, enhancing the efficiency of cognitive and motor training, providing neurorecovery and neurorehabilitation, enhancing the efficiency of nonhuman animal training protocols, and treating treating peripheral disorders, including 10 inflammatory and renal disorders.
