Bollu, Venkataiah,Breitenbucher, James,Kaplan, Alan,Lemus, Robert,Lindstrom, Andrew,Vickers, Troy,Wilson, Mark E.,Zapf, James,Weinhouse, Michael I.
申请号:
AU2014241430
公开号:
AU2014241430A1
申请日:
2014.03.06
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The invention provides a chemical entity of Formula (I), and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies, detection and imaging techniques, and radioactive treatments; and therapies, including inhibiting PDE4, enhancing neuronal plasticity, treating neurological disorders, providing neuroprotection, treating a cognitive impairment associated with a CNS disorder, enhancing the efficiency of cognitive and motor training, providing neurorecovery and neurorehabilitation, enhancing the efficiency of non- human animal training protocols, and treating treating peripheral disorders, including inflammatory and renal disorders.