吡啶並嘧啶或嘧啶並嘧啶類化合物、其製備方法、藥物組合物及其用途

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专利权人:

Shanghai Institute of Materia Medica Chinese Acade

发明人:

SHEN, Jingkang,YU, Ke,MENG, Tao,MA, Lanping,ZASK, Arie,MENG, Lanfang,WANG, Xin,CHEN, Yiyi

申请号：

HK16105194.5

公开号：

HK1217197A

申请日:

2016.05.06

申请国别(地区):

HK

年份:

2016

代理人:

摘要：

The present invention belongs to the field of pharmaceutical Chemistry. In particular, the present invention relates to a pyridopyrimidine or pyrimidopyrimidine compound as represented by general formula (I), or an isomer thereof or a pharmaceutical acceptable salt, ester, prodrug or solvate thereof, a preparation method, a pharmaceutical composition and uses thereof in preparing a mTOR inhibitor. As a mTOR inhibitor, the compound or the pharmaceutical composition thereof can be used for treating a disease or condition due to PI3K-AKT-mTOR signalling pathway malfunction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/