The present invention is directed to methods and systems for reducing lipopolysaccharides on medical devices and fluids that are intended to be in contact with the human body or to be inside of the human body. In on embodiment, the present invention relates to methods for treating solutions containing one or more endotoxins at detectable levels by adding a suspension of a stearate, preferably calcium stearate, to said solution to reduce detectable amounts of said endotoxins: and optionally removing the stearate. The present invention is also directed to methods for treating medical devices and methods of treatment by contacting the devices or tissue surfaces of a mammal with a stearate suspension to reduce detectable amounts of endotoxins on said mammal.
