John W. LAMPE,Tomas NAVRATIL,Ward M. PETERSON,Jose L. BOYER,Emilee H. FULCHER,Scott D. SORENSEN
申请号：
US13774869
公开号：
US20130172324A1
申请日:
2013.02.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention is directed to methods of preventing or treating diseases or conditions associated with excessive cell proliferation, remodeling, inflammation, and vasoconstriction. Particularly, this invention is directed to methods of treating cardiovascular diseases or conditions such as stent restenosis and thrombosis, vascular thrombosis, cerebral vasospasm, atherosclerosis, systemic hypertension, cardiac hypertrophy, and sexual dysfunction. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel Rho kinase inhibitor compound to treat the disease.
