МИТЧЕЛЛ Хелен (US),ФРЭЛИ Марк Э. (US),КУК Эндрю Дж. (US),СТАМП Крейг А. (US),ЧЭНЬ И Хэн (US),БИШОР Дуглас С. (US),ЧЖАН Сюй-Фан (US),МакКОМАС Кейси С. (US),ШИРРИПА Кэти (US),МакВЕРТЕР Мелоди (US),МЕРСЕ
申请号：
RU2016141645
公开号：
RU2016141645A
申请日:
2015.03.23
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
