UTILISATION DE LIPASE ACIDE LYSOSOMALE POUR TRAITER UN DEFICIT EN LIPASE ACIDE LYSOSOMALE CHEZ DES PATIENTS

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专利权人:

SYNAGEVA BIOPHARMA CORP;SYNAGEVA BIOPHARMA CORP.

发明人:

QUINN, ANTHONY

申请号：

CA2810999

公开号：

CA2810999A1

申请日:

2011.09.09

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The present invention provides treating LAL deficiency (e.g. Wolman's disease, CESD) comprising administering to a mammal a therapeutically effective amount o lysosomal acid lipase with an effective dosage frequency. Methods of improving growth and liver function, increasing LAL tissue concentration, and increasing LAL activity in a human patient suffering from LAL deficiency are also provided

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