Napo Pharmaceuticals, Inc.;The Regents of the University of California
发明人:
Verkman, Alan S.,Chaturvedi, Pravin,Tradtrantip, Lukmanee,Namkung, Wan
申请号:
AU2010303577
公开号:
AU2010303577B2
申请日:
2010.10.05
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Disclosed herein are methods of treating diseases including gastrointestinal disorders, such as secretory diarrheas, with the proanthocyanidin oligomer, crofelemer. Also disclosed is the anti-secretory effect of crofelemer on Calcium-activated chloride channels (CaCC) and Cystic fibrosis transmembrane conductance regulator (CFTR).