Lukmanee Tradtrantip;Alan S. Verkman;Pravin Chaturvedi;Wan Namkung
发明人:
Alan S. Verkman,Pravin Chaturvedi,Lukmanee Tradtrantip,Wan Namkung
申请号：
US13500589
公开号：
US20120202876A1
申请日:
2010.10.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are methods of treating diseases including gastrointestinal disorders, such as secretory diarrheas, with the proanthocyanidin oligomer, crofelemer. Also disclosed is the anti-secretory effect of crofelemer on Calcium-activated chloride channels (CaCC) and Cystic fibrosis transmembrane conductance regulator (CFTR).
