ANTICORPS ANTI-CD25 POUR LA DEPLETION DE CELLULES SPECIFIQUES D'UNE TUMEUR

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专利权人:

TUSK THERAPEUTICS LTD;CANCER RESEARCH TECHNOLOGY LIMITED

发明人:

GOUBIER, ANNE,GOYENECHEA CORZO, BEATRIZ,SALIMU, JOSEPHINE,MOULDER, KEVIN,MERCHIERS, PASCAL,BROWN, MARK,GEOGHEGAN, JAMES,PRINZ, BIANKA,QUEZADA, SERGIO

申请号：

CA3088659

公开号：

CA3088659A1

申请日:

2019.03.13

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a- 646 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitope : PHATFKAMA YKEGTM (42-56) on CD25. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.

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