Anti-CD25 for tumour specific cell depletion

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专利权人:

Tusk Therapeutics Ltd;Cancer Research Technology Limited

发明人:

GOUBIER, Anne,GOYENECHEA CORZO, Beatriz,SALIMU, Josephine,MOULDER, Kevin,MERCHIERS, Pascal,BROWN, Mark,GEOGHEGAN, James,PRINZ, Bianka,QUEZADA, Sergio

申请号：

AU2019233576

公开号：

AU2019233576A1

申请日:

2019.03.13

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a- 646 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitope : PHATFKAMA YKEGTM (42-56) on CD25. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.

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