David Robbins,Betsy Rezner,Leah Mitchell,Lisa Guerrettaz,Philippe Alessandro Parone,Robert Steven Tacke,Kevin Lai,Bahram Valamehr
申请号:
US15546255
公开号:
US20180112180A1
申请日:
2016.01.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is directed to compositions and methods to increase the expression of PD-L1 and/or IDO-1 in a population of cells, the modulated cells expressing increased PD-L1 and/or IDO-1, and methods related to the immunosuppressive effects obtained by cells expressing increased PD-L1 and/or IDO-1.