Robbins, David,Rezner, Betsy,Mitchell, Leah,Guerrettaz, Lisa,Parone, Philippe Alessandro,Tacke, Robert Steven,Lai, Kevin,Valamehr, Bahram
申请号:
AU2016211688
公开号:
AU2016211688A1
申请日:
2016.01.26
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention is directed to compositions and methods to increase the expression of PD-L1 and/or IDO-1 in a population of cells, the modulated cells expressing increased PD-L1 and/or IDO-1, and methods related to the immunosuppressive effects obtained by cells expressing increased PD-L1 and/or IDO-1.