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SELS ADJUVANTS D'AMINES CONTENANT DES GROUPES HYDROXYLE ET/OU CARBONYLE AVEC DES DÉRIVÉS D'ACIDES AMINONICOTIQUES EN TANT QU'INHIBITEURS DE LA DHODH
专利权人:
ALMIRALL S.A.
发明人:
申请号:
EP10708932.8
公开号:
EP2406225B1
申请日:
2010.03.11
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention is directed to novel water-soluble pharmaceutically acceptable, crystalline addition salts of (i) an amine containing one or more hydroxyl and/or carboxylic groups with (ii) amino nicotinic acid derivatives of formula (I) wherein R a , R b , R c and R d independently represent groups selected from hydrogen atoms, halogen atoms, C 1-4 alkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C 1-4 alkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and pharmaceutically acceptable solvates thereof.
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