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DERIVES DE 1-H-PYRROLE SUBSTITUES PAR UN GROUPE 1-HETEROCYCLYLSULFONYLE, 2-AMINOMETHYLE, 5-(HETERO)ARYLE EN TANT QU'INHIBITEURS DES SECRETIONS ACIDES
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
KAJINO, MASAHIRO,HASUOKA, ATSUSHI,NISHIDA, HARUYUKI
申请号:
CA2621182
公开号:
CA2621182C
申请日:
2006.08.29
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention provides a compound having a superior acid secretioninhibitory effect and showing an antiulcer activity and the like. The presentinvention provides a compound represented by the formula (I) wherein R1 is anitrogen-containing monocyclic heterocyclic group optionally condensed with abenzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclicgroup optionally condensed with a benzene ring or a heterocycle optionally hassubstituent(s), R2 is an optionally substituted C6-14 aryl group, anoptionally substituted thienyl group or an optionally substituted pyridylgroup, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogenatom and the other is an optionally substituted lower alkyl group, an acylgroup, a halogen atom, a cyano group or a nitro group, and R5 is an alkylgroup or a salt thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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