Klaus Rudolf,Daniel Bischoff,Georg Dahmann,Matthias Grauert,Raimund Kuelzer
申请号：
US13707715
公开号：
US08846948B2
申请日:
2012.12.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention relates to compounds of formula Itheir use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3, R3a have meanings given in the description.
