An ocular iontophoresis device for delivering a medication, comprises a medication reservoir suitable for being positioned on an eye medication(s) in solution in the reservoir an active electrode disposed in the reservoir and a passive electrode. The medication is dissolved in non-saline water. It includes an active principle associated with an additive, e.g. a dendrimer, a polymer, a nanoparticle, a microsphere, a liposome or an emulsion. An ocular iontophoresis device (1) for delivering a medication, comprises a medication reservoir (20) suitable for being positioned on an eye medication(s) (30) in solution in the reservoir an active electrode (10) disposed in the reservoir and a passive electrode (40). The medication is dissolved in non-saline water. The solution has a pH of 6.5-8.5. The medication includes an active principle associated with an additive, e.g. a dendrimer, a polymer, a nanoparticle, a microsphere, a liposome, or an emulsion. It has a pKa of 5.5-9.5, and an ionic form of valency of >=1. An independent claim is also included for a method of treatment by ocular iontophoresis, comprising positioning the above iontophoresis device on the eye to deliver medication and implementing ocular iontophoresis by using the iontophoresis device.Linvention concerne un dispositif de iontophorèse oculaire (1) permettant dadministrer un médicament dans un oeil et comprenant : un réservoir (20), le réservoir ayant une extrémité proximale et une extrémité distale, lextrémité proximale comprenant une lèvre souple (21) pouvant entrer en prise avec loeil afin dadministrer le médicament une électrode active (10) disposée tout près de lextrémité distale du réservoir, lélectrode active étant incurvée et présentant un rayon de courbure interne proche du rayon de courbure de la cornée de loeil et un médicament stocké dans le réservoir.
