한국과학기술연구원;KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
发明人:
PAE, AE NIM,배애님,MIN, SUN JOON,민선준,ROH, EUN JOO,노은주,YANG, HA YUN,양하연,KIM, TAE HOON,김태훈,PARK, BEOUNG GUN,박병건,CHO, YONG SEO,조용서
申请号：
KR1020120117057
公开号：
KR1020140050802A
申请日:
2012.10.22
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
The present invention relates to a benzimidazole derivative which has pharmaceutical activity as a neuroprotective agent by modulating mitochondrial functions and a pharmaceutical composition comprising the same as an active ingredient. The benzimidazole derivative or a pharmaceutically acceptable salt thereof, according to the present invention, has an excellent activity as a neuroprotective agent affecting mitochondria, thereby can be used as a medicine for diseases such as Alzheimer&prime；s disease, Parkinson&prime；s disease, Huntington&prime；s disease, ischemic brain disease, diabetes, and schizophrenia.본 발명은 미토콘드리아의 기능을 조절하여 신경보호제로서의 약학적 활성을 보이는 벤즈이미다졸 유도체, 및 이 화합물이 유효성분으로 함유된 약제조성물에 관한 것이다.
