Sudhakar Kadiyala,Patrick Lim Soo,Mark Iwicki,Craig A. Dunbar,Mark T. Bilodeau,Rajesh R. Shinde,Rossitza G. Alargova,Michelle Dupont
申请号:
US14908661
公开号:
US20160166715A1
申请日:
2014.07.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to the use of in vivo contrast agents in medical imaging in order to diagnose and treat disease, and to monitor and assess disease progression following treatment with a nanoparticle therapeutic agent comprising an active pharmaceutical agent. The present invention also relates to modulating nanoparticle tumor concentration by modulating the PEG density of the nanoparticles.