PROBLEM TO BE SOLVED: To provide a method for effectively screening an agent for effectively preventing and/or treating a disease.SOLUTION: According to the present invention, a method for screening an agent for preventing and/or treating a disease according to an embodiment of the present invention comprises the following steps (1) and (2): (1) a step of preparing one or more substances that inhibit a signal transduction system of c-Abl and (2) a step of selecting one or more substances that inhibit uptake of an extracellular macromolecule by cells out of the one or more substances as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】疾患の予防及び/又は治療剤の効果的なスクリーニング方法を提供する。【解決手段】本発明の一実施形態に係る疾患の予防及び/又は治療剤のスクリーニング方法は、下記工程(1)及び(2)を含む:(1)c-Ablのシグナル伝達系を抑制する1以上の物質を用意する工程;及び(2)前記1以上の物質のうちから、細胞外の高分子の細胞による取り込みを抑制する1以上の物質を、前記有効成分として選択する工程。【選択図】なし
