Sushrut Krishnaji KULKARNI,Ajaykumar HANDA,Amit Om Prakash GUPTA
申请号:
US15019094
公开号:
US20160235776A1
申请日:
2016.02.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a sustained release composition comprising topiramate and one or more pharmaceutical excipients, wherein the composition comprises a single population of beads, wherein each bead comprises: a) an inert core, b) an inner layer comprising topiramate, c) an outer layer comprising at least one sustained release material and at least one alkalizer. It also relates to methods of preparing such compositions and using those compositions in the treatment of neurological and/or psychiatric condition.