CRISTAL COMPRENANT UN ACIDE (2R)-2-PROPYLOCTANOIQUE ET DIBENZYLAMINE

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专利权人:

ONO PHARMACEUTICAL CO.; LTD.

发明人:

申请号：

EP05739057.7

公开号：

EP1741697B1

申请日:

2005.04.27

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

According to the present invention, crystals comprising (2R)-2-propyloctanoic acid and an amine, which can be used as bulk drugs for safely orally administrable solid preparations with keeping the pharmacological effect, are provided. Among these crystals, the crystal with dibenzylamine per se is particularly useful as bulk drug for pharmaceuticals and can be used as an intermediate to produce (2R)-2-propyloctanoic acid having an optical purity of more than 99.5%e.e. which has not been obtained.

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