Lu, Timothy Kuan-Ta,Gordley, Russell Morrison,Lin, Jack Tzu-Chiao,Garrison, Brian Scott,Lee, Philip Janmin,Gonzalez-Junca, Alba,Wang, Don-Hong
申请号：
AU2018251898
公开号：
AU2018251898A1
申请日:
2018.04.13
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
