LU, TIMOTHY KUAN-TA,GORDLEY, RUSSELL MORRISON,LIN, JACK TZU-CHIAO,GARRISON, BRIAN SCOTT,LEE, PHILIP JANMIN,GONZALEZ-JUNCA, ALBA,WANG, DON-HONG
申请号：
CA3059634
公开号：
CA3059634A1
申请日:
2018.04.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.
