In the prevention and/or treatment of a neuropsychiatric disease or a peripheral organ disease and the like, a pharmaceutical which comprises a compound having CRF antagonistic activity as an active ingredient is provided. A compound of a formula (I): wherein R 1 represents a C3-10 branched alkyl group which may be substituted； R 2 represents a hydrogen atom or a C1-4 alkyl group which may be substituted； R 3 represents a C1-4 alkyl group which may be substituted or a halogen atom； R 4 represents a C1-4 alkyl group which may be substituted； and ring 1 represents a cyclic group which has planarity and may have a substituent group, a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof, is useful as a medicinal component having CRF antagonistic activity for the prevention and/or treatment of a neuropsychiatric disease, a peripheral organ disease and the like.
