BIEMANS, BARBARA,GUBA, WOLFGANG,JAESCHKE, GEORG,RICCI, ANTONIO,RUEHER, DANIEL,VIEIRA, ERIC
申请号：
PH12016501100
公开号：
PH12016501100A1
申请日:
2016.06.09
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
The present invention relates to compounds of formula (I) wherein Y is C-R1 R1 is hydrogen or halogen R1 is hydrogen or halogen R2 is hydrogen, lower alkyl or phenyl, R4 is hydrogen or lower alkyl or R2 and R4 may form together with the corresponding atoms, to which they are attached the following rings: (A), (B), (C), (D) or (E) R5 is hydrogen or lower alkyl and if R2 and R4 form a ring as described above, than R5 is hydrogen or R4 and R5 may form together with the C-atom to which they are attached a heterocycloalkyl ring R3 is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be in different positions or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. The compounds may be used for the treatment of Parkinsons disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.
