BLOKHIN, ANDREI, V.,ROZEMA, DAVID, B.,BENSON, JONATHAN, D.,CARLSON, JEFFREY, C.
申请号:
EP12801275
公开号:
EP2720540A4
申请日:
2012.05.31
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.