DISUBSTITUTED MALEIC ANHYDRIDES WITH ALTERED KINETICS OF RING CLOSURE

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专利权人:

发明人:

申请号：

EP12801275.4

公开号：

EP2720540A1

申请日:

2012.05.31

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.

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