Douglas S. KIM,Loren L. LOOGER,Eric R. SCHREITER,Karel SVOBODA
申请号：
US15461603
公开号：
US20170198015A1
申请日:
2017.03.17
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Protein indicators useful for calcium imaging, in particular, red genetically-encoded calcium indicators (GECIs) disclosed herein rival best-of-class green GECIs in terms of sensitivity for detecting neural activity, and can be monitored in vivo. The presently-disclosed subject matter further includes a method of monitoring cell activity comprising stimulating a cell comprising a red GECI polypeptide and detecting fluorescence emitted by the cell.
