KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;SEOUL NATIONAL UNIVERSITY R&；DB FOUNDATION
发明人:
In Pyo CHOI,Tae-Don KIM,Su Ui LEE,Sooyun LEE,Junho CHUNG,Ki-Hyun KIM
申请号：
US16503984
公开号：
US20190365815A1
申请日:
2019.07.05
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed are a natural killer (NK) cell expressing an anti-cotinine chimeric antigen receptor (CAR) specifically binding to cotinine, and a cell therapeutic agent containing the NK cell. The CAR-expressing NK cell which specifically binds cotinine, can effectively move to tumor tissue, regardless of the kind of cancer, depending on the binding substance bound to cotinine. Therefore, the natural killer cell can be usefully employed as a gene therapy exhibiting a highly efficient anticancer effect.
