National University of Singapore;St. Jude Children's Research Hospital, Inc.
发明人:
Dario Campana,David Shook,Masaru Imamura
申请号：
US16550548
公开号：
US20190376037A1
申请日:
2019.08.26
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides, in certain aspects, a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15), and methods for producing such cells. The invention further provides methods of using a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15) to treat cancer in a subject or to enhance expansion and/or survival of NK cells.
