Leppanen, Anne,Ekholm, Filip S.,Helin, Jari,Salo, Hanna,Kanerva, Anne
申请号:
AU2015273353
公开号:
AU2015273353A1
申请日:
2015.06.12
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to a conjugate comprising an anti-EGFR1 antibody or an EGFR binding fragment thereof and at least one dextran derivative, wherein the dextran derivative comprises at least one D-glucopyranosyl unit, wherein at least one carbon selected from carbon 2, 3 or 4 of the at least one D-glucopyranosyl unit is substituted by a substituent of the formula -O-(CH