Provided is a control device, an endoscope system, a processing method, and a program which can select a region other than the center region in an image to perform a predetermined process. An endoscope system 1 includes an image generation unit 92 which processes an image signal generated by an imaging unit 54 to generate a display image to be displayed, a display controller 95a which overlaps a plurality of select regions selectable according to an external operation to the display image and outputs the overlapped image to the display device 7, and an AF controller 612 which performs a predetermined process on at least one select region selected according to the external operation.