INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION;AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
Ki Dong PARK,Kyung Min PARK,Yun Ki LEE,Thi Thai Thanh HOANG,Thi Phuong LE
申请号:
US15475948
公开号:
US20170281781A1
申请日:
2017.03.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided are an injectable tissue adhesive hydrogel including gamma-cyclodextrin (γ-CD). When such an injectable tissue adhesive hydrogel including the γ-CD is used as a skin glue, based on a fact that the γ-CD has a bigger hydrophobic cavity than that of α- and β-CDs, the injectable tissue adhesive hydrogel including the γ-CD has stronger interactions than host-guest interactions. In addition, hydrogen bonding in the injectable tissue adhesive hydrogel including the γ-CD can improve both cohesiveness and adhesiveness of gelatin. The injectable tissue adhesive hydrogel including the γ-CD having excellent cell viability is used for adhesion of a skin incision, to thereby effectively promote tissue regeneration.