INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);UNIVERSITÉ PARIS DESCARTES - PARIS V;UNIVERSITE PARIS DIDEROT;SORBONNE UNIVERSITE;SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT
发明人:
Fleur BERES,Gilles RICHARD,Arnaud DESSOMBZ,Stéphane SIMON,Juliane ISAAC
申请号：
US16604442
公开号：
US20200155725A1
申请日:
2018.04.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, including: a porous polymer matrix having interconnected pores； and non-hydrated calcium silicate particles； wherein: the polymer matrix is anhydrous； the non-hydrated calcium silicate particles have a d50 granulometry, preferably ranging from 0.05 μm to less than the average diameter size of the pores of the matrix； and the non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. Also, a method for preparing the connective tissue regenerative material and uses of the regenerative materials, such as in the dental field； especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e. good migration, adhesion and proliferation of cells； enhanced mechanical properties； and optimal and controlled biodegradability).
