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COMBINATION OF PI3K INHIBITOR AND C-MET INHIBITOR
专利权人:
Novartis AG
发明人:
Giordano Caponigro,XIZHONG Huang,Joseph Lehar,Hui-Qin Wang
申请号:
US16820886
公开号:
US20200253980A1
申请日:
2020.03.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to a pharmaceutical combination which comprises (a) a phosphatidylinositol 3-kinase inhibitor or pharmaceutically acceptable salt thereof, and (b) at least one c-Met receptor tyrosine kinase inhibitor or pharmaceutically acceptable salt thereof, for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly a c-Met dependent proliferative disease; a pharmaceutical composition comprising such combination; a method of treating a subject having a proliferative disease comprising administration of said combination to a subject in need thereof; use of such combination for the treatment of proliferative disease; and a commercial package comprising such combination.
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