Giordano Caponigro,Xizhong Huang,Joseph Lehar,Hui-Qin Wang
申请号:
US14420792
公开号:
US20150216870A1
申请日:
2013.08.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a pharmaceutical combination which comprises (a) a phosphatidylinositol 3-kinase inhibitor or pharmaceutically acceptable salt thereof, and (b) at least one c-Met receptor tyrosine kinase inhibitor or pharmaceutically acceptable salt thereof, for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly a c-Met dependent proliferative disease a pharmaceutical composition comprising such combination a method of treating a subject having a proliferative disease comprising administration of said combination to a subject in need thereof use of such combination for the treatment of proliferative disease and a commercial package comprising such combination.