PURPOSE: A composition containing Ixeris dentata Nakai extract for preventing and treating dermatitis is provided to prevent skin barrier damage and to suppress hypersensitivity of IL-1 beta.CONSTITUTION: A pharmaceutical composition for preventing and treating dermatitis contains Ixeris dentata Nakai extract as an active ingredient. The extract reduces IgE and IL-1beta amount in blood. An agent for preventing and treating dermatitis contains the extract as an active ingredient. The agent is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, aerosol, suppository, or sterilized injection solution by adding pharmaceutically acceptable carriers, excipients, or diluents. A health functional food for preventing and treating dermatitis contains the extract as an active ingredient and sitologically acceptable food additives.COPYRIGHT KIPO 2013본 발명은, 아토피성 피부염 및 접촉성 피부염을 포함하는 피부질환에서, 피부의 장벽 기능이 손상되지 않게 할 뿐더러, 이뮤노글로블린 E(IgE)가 과민 반응하는 것을 억제하고, 염증성 사이토카인인 인터루킨-1β가 과잉 분비되는 것을 억제함으로써, 피부질환을 예방, 개선 및 치료하기 위한 조성물에 관한 것이다.본 발명인 피부질환의 예방, 개선 및 치료를 위한 조성물은 씀바귀 추출물을 유효성분으로 포함함에 기술적 특징이 있다.
