John J. Shay, Jr.;Patrick Wai-Kwok Shum;Adam W. Sledeski;Yong Mi Choi-Sledeski;Nakyen Choy;Gregory Bernard Poli
发明人:
Yong Mi Choi-Sledeski,Nakyen Choy,Gregory Bernard Poli,John J. Shay, Jr.,Patrick Wai-Kwok Shum,Adam W. Sledeski
申请号：
US13028745
公开号：
US08217178B2
申请日:
2011.02.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to an indole benzylamine compound of formula I:useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.
