PROBLEM TO BE SOLVED: To provide a method for conveniently producing an assembly of regenerative hair follicle germs that resemble hair follicle tissues of mammals, are arranged regularly and in high density, and have microvascular structures inside.SOLUTION: The present invention provides a method for producing an assembly of regenerative hair follicle germs having microvascular structures. The method has the step in which: on a micro recess plate having fine recesses regularly arranged, seeded are cells that can construct mesenchymal cells, epithelial cells, and blood vessels while supplied with oxygen, they are mixedly cultured, to form hair follicle germs.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】哺乳動物の毛包組織と類似し、規則的且つ高密度の内部に毛細血管構造を有する再生毛包原基の集合体を簡便に製造する方法を提供する。【解決手段】本発明の毛細血管構造を有する再生毛包原基の集合体の製造方法は、規則的な配置の微小凹部からなるマイクロ凹版に、間葉系細胞、上皮系細胞、及び血管を構築し得る細胞を播種し、酸素を供給しながら混合培養することにより、毛包原基を形成させる工程を備える。【選択図】なし
