MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人:
Jens O. Watzlawik,Arthur E. Warrington,Moses Rodriguez,William A. Carey
申请号：
US15524058
公开号：
US20170355754A1
申请日:
2015.11.06
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention provides methods for the treatment of neonatal hypoxia and associated white matter disease or injury, particularly in infant, including neonatal, animals, particularly Periventricular Leukomalacia (PVL) comprising administering one or more CNS reactive antibody, particularly selected from IgM12, IgM22, IgM42 and IgM46. Compositions for use in treatment of white matter disease or injury in infants, particularly PVL are provided. The invention provides methods for alleviation of neuromotor or neurodevelopmental deficits associated with neonatal hypoxia and associated with white matter injury, including PVL, in an infant.
