HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH);IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.;THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人:
ZISCHKA, HANS,LICHTMANNEGGER, JOSEF,DISPIRITO, ALAN ANGELO,SEMRAU, JEREMY DAVID
申请号:
CA3000792
公开号:
CA3000792A1
申请日:
2016.12.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other conditions.