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Modular DNA-binding domains and methods of use
专利权人:
Ulla Bonas
发明人:
Ulla Bonas,Jens Boch,Sebastian Schornack,Thomas Lahaye
申请号:
US13362660
公开号:
US08420782B2
申请日:
2012.01.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of the polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.
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