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Modular DNA-binding domains and methods of use
专利权人:
Jens Boch;Sebastian Schornack;Ulla Bonas;Thomas Lahaye
发明人:
Ulla Bonas,Jens Boch,Sebastian Schornack,Thomas Lahaye
申请号:
US13218050
公开号:
US08470973B2
申请日:
2011.08.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of the polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.
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