Jay R. Lieberman,William Pannell,Yong Chen,Xuan Song,Sofia Bougioukli
申请号：
US16337893
公开号：
US20200022816A1
申请日:
2017.09.29
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method for repairing a bone defect of a patient includes providing a ceramic scaffold configured for filling the bone defect, loading the scaffold with growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation, placing the ceramic scaffold with the growth factor transduced cells in or across the bone defect, and stabilizing the ceramic scaffold with the growth factor transduced cells in the patient until the bone defect is healed. An assembly for repairing a bone defect includes a ceramic scaffold configured for spanning the bone defect and a culture of live growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation loaded onto the ceramic scaffold.
