Substituted indole derivatives of formula (I)wherein the radicals have e.g. the following meaning:R1 is hydrogen, —C1-6-alkyl, R2 is hydrogen, —C1-6-alkyl or cycloC3-12-alkyl；R3 is —ORR4 is hydrogen or halogen,R5 is hydrogen, —C1-6-alkylR6 is hydrogen, —C1-6-alkylR is hydrogen or —C1-6-alkyl；X is a group —C(O)CH2— or —CH═CH—；R7 is hydrogenare potent inhibitors of Abeta peptide polymerization and can be used for the treatment of e.g. Alzheimers disease or ocular disorders.
